A postdoctoral fellow position is immediately available in the laboratory of Dr. Fadia Ibrahim in the Department of Biochemistry and Molecular Biology, at Thomas Jefferson University. Our research program is focused on studying the molecular mechanism of co-translational mRNA decay, and investigating the role of RNA dysregulation in neurodegenerative diseases including amyotrophic lateral sclerosis. We use a combination of molecular biology, cell biology, and biochemistry techniques, and advanced and novel high-throughput RNA sequencing methods. This position seeks a highly motivated computational biologist to provide bioinformatics support for ongoing studies, setup/develop and implement bioinformatics tools and pipelines, and manage all aspects of data analysis and processing of complex short- and long-sequencing reads

https://www.jefferson.edu/university/jmc/departments/biochemistry/facultystaff/faculty/ibrahim.html/publications

• Ph.D. in computational biology, bioinformatics, biomedical/biological engineering, computational sciences, or related disciplines.
• Proficiency in R and Python, other programming languages are an advantage.
• Knowledge of fundamental concepts in biology, and/or knowledge of techniques commonly used in biological labs, such as nucleic acids electrophoresis, PCR, and cell culture.
• Knowledge of statistics to properly apply and perform relevant statistical tests.
• Knowledge of high-throughput sequencing technologies (e.g. Illumina, ONT) and their application to specific biological problems, and awareness of their strength and weaknesses.
• Experience in -omics data processing and analysis (e.g. RNA-Seq, small RNA-Seq, RiboSeq) and data interpretation/evaluation (e.g. differential expression, ribosome occupancy, peak calling).
• Ability to integrate, mine, and analyze complex biological data.
• Experience with common bioinformatics resources, tools, and databases, such as ENCODE, UCSC Genome Browser, Bioconductor, and NCBI databases.
• Efficiency in Linux/Unix environment. Experience with management of server and data storage is an advantage.
• Development of scientific hypothesis related to ongoing research in the laboratory.
• Commitment to delivering high-quality results.
• Strong analytical skills and ability to plan analysis steps independently.
• Strong organization, time management, communication and presentation skills.
• Ability to work effectively in a team environment.
• Publication record in peer-reviewed journals.

Jefferson includes Thomas Jefferson University and Jefferson Health, a dynamic university and health system with broad reach across the Delaware Valley. Jefferson is the second largest employer in Philadelphia and the largest health system in Philadelphia based on total licensed beds.

Through the merger of Thomas Jefferson University and Philadelphia University in 2017, our University includes ten colleges and four schools. We are an NCAA Division II university and an R2 national doctoral university offering undergraduate and graduate-level programs that provide students with a forward-thinking education in architecture, business, design, engineering, fashion and textiles, health, medicine and social science.

Jefferson Health, the clinical arm of Thomas Jefferson University, has grown from a three-hospital academic health center in 2015, to an 18-hospital health system through mergers and combinations that include hospitals at Abington Health, Aria Health, Kennedy Health, Magee Rehabilitation and Einstein Healthcare Network. We have over 50 outpatient and urgent care centers; ten Magnetreg;-designated hospitals (recognized by the ANCC for nursing excellence); the NCI-designated Sidney Kimmel Cancer Center (one of only 70 in the country and one of only two in the region); and one of the largest faculty-based telehealth networks in the country. In 2021, Jefferson Health became the sole owner of HealthPartners Plan, a not-for-profit health maintenance organization in Southeastern Pennsylvania. We are the first health system regionally to create an aligned payer-provider partnership.

Jeffersonrsquo;s mission, vision and values create an organization that attracts the best and the brightest students, faculty, staff, and healthcare professionals, as well as the most visionary leaders to drive exceptional results.

• OUR MISSION: We improve lives.
• OUR VISION: Reimagining health, education and discovery to create unparalleled value
• OUR VALUES: Put People First, Be Bold amp; Think Differently and Do the Right Thing

As an employer, Jeffersonmaintains a commitment to provide equal access to employment. Jefferson values diversity and encourages applications from women, members of minority groups, LGBTQ individuals, disabled individuals, and veterans.