PRIMARY FUNCTION:

The roles of platelet microvesicles and microRNAs in thrombo-inflammation

A Postdoctoral fellow position is available for candidates to contribute to characterize the roles and mechanisms of platelet-derived extracellular vesicles and platelet microRNAs, in platelet-leukocyte interactions and immune responses in inflammatory settings of high clinical relevance. Approaches will include various ex vivo analysis of blood cell functions, cell biological studies of blood cell response, and in vivo models of thrombosis and inflammation. The candidate must have experience with molecular and cellular biology. A background in genetics, benign hematology/blood physiology, and experience with working with animal models will be viewed favorably. This position provides an excellent opportunity to grow scientifically and work with a dynamic group of investigators studying important and exciting aspects of vascular thrombosis and thrombo-inflammation.

ESSENTIAL FUNCTIONS:

• Handling human blood and platelets
• Experience with western blotting and traditional cell and molecular biology techniques
• An understanding of biochemistry and pharmacology
• Ability to learn new biochemical and physiological techniques
• Ability to work independently
• Participate in supervision of graduate students
• Ability to present work at national meetings, prepare manuscripts for submission
• Minimum 2 to 3 year commitment
• Interacts with co-workers, visitors, and other staff consistent with the core values of the University.

Applicant should have a PhD or MD in biology, molecular biology, cell biology, physiology, biochemistry, vascular biology, or a relevant discipline, and demonstrated expertise evidenced by a strong publication record. Applicants with an MD with relevant research experience and a strong interest in basic and translational research will also be considered.

Covid Vaccination is a requirement for employment at Jefferson for employees working at Jeffersonrsquo;s clinical entities or at the University. If you are not currently vaccinated you will be required to receive the vaccination prior to hire date if you are offered employment, unless you request and receive an approved medical or religious exemption from Jefferson.

Jefferson includes Thomas Jefferson University and Jefferson Health, a dynamic university and health system with broad reach across the Delaware Valley. Jefferson is the second largest employer in Philadelphia and the largest health system in Philadelphia based on total licensed beds.

Through the merger of Thomas Jefferson University and Philadelphia University in 2017, our University includes ten colleges and four schools. We are an NCAA Division II university and an R2 national doctoral university offering undergraduate and graduate-level programs that provide students with a forward-thinking education in architecture, business, design, engineering, fashion and textiles, health, medicine and social science.

Jefferson Health, the clinical arm of Thomas Jefferson University, has grown from a three-hospital academic health center in 2015, to an 18-hospital health system through mergers and combinations that include hospitals at Abington Health, Aria Health, Kennedy Health, Magee Rehabilitation and Einstein Healthcare Network. We have over 50 outpatient and urgent care centers; ten Magnetreg;-designated hospitals (recognized by the ANCC for nursing excellence); the NCI-designated Sidney Kimmel Cancer Center (one of only 70 in the country and one of only two in the region); and one of the largest faculty-based telehealth networks in the country. In 2021, Jefferson Health became the sole owner of HealthPartners Plan, a not-for-profit health maintenance organization in Southeastern Pennsylvania. We are the first health system regionally to create an aligned payer-provider partnership.

Jeffersonrsquo;s mission, vision and values create an organization that attracts the best and the brightest students, faculty, staff, and healthcare professionals, as well as the most visionary leaders to drive exceptional results.

• OUR MISSION: We improve lives.
• OUR VISION: Reimagining health, education and discovery to create unparalleled value
• OUR VALUES: Put People First, Be Bold amp; Think Differently and Do the Right Thing

As an employer, Jeffersonmaintains a commitment to provide equal access to employment. Jefferson values diversity and encourages applications from women, members of minority groups, LGBTQ individuals, disabled individuals, and veterans.